Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
نویسندگان
چکیده
منابع مشابه
Stress increases vulnerability to inflammation in the rat prefrontal cortex.
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because sensitivity to inflammation is not equal in all brain structures, a direct relationship is not clear. Our aim was to test whether some physiological circumstances, such as stress, could enhance susceptibility to inflammation in the prefrontal cortex (PFC), which shows a rela...
متن کاملP142: The Prefrontal Cortex and Stress-Related Psychopathologies
The prefrontal cortex (PFC) plays a central role in processing both normal and pathological affective states and it is among the brain regions most closely associated with stress-related psychopathology in humans. The ventromedial PFC (vmPFC) in particular has been shown to be required for healthy emotional regulation, social function and risk assessment and decision-making. Also this region ex...
متن کاملPS197. Low level of perineuronal nets in the medial prefrontal cortex predicts vulnerability to stress
Objectives: The purpose of this study is to investigate the alterations of the hypothalamic-pituitary-adrenal axis hormones, especially salivary cortisol and dehydroepiandrosterone (DHEA) in perinatal depression. Methods: 44 patients with depression and 217 normal subjects in perinatal period were included in this study. Edinburgh Postnatal Depression Scale(EPDS) and Beck Depression Inventory I...
متن کاملChronic stress alters dendritic morphology in rat medial prefrontal cortex.
Chronic stress produces deficits in cognition accompanied by alterations in neural chemistry and morphology. Medial prefrontal cortex is a target for glucocorticoids involved in the stress response. We have previously demonstrated that 3 weeks of daily corticosterone injections result in dendritic reorganization in pyramidal neurons in layer II-III of medial prefrontal cortex. To determine if s...
متن کاملp142: the prefrontal cortex and stress-related psychopathologies
the prefrontal cortex (pfc) plays a central role in processing both normal and pathological affective states and it is among the brain regions most closely associated with stress-related psychopathology in humans. the ventromedial pfc (vmpfc) in particular has been shown to be required for healthy emotional regulation, social function and risk assessment and decision-making. also this region ex...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2006
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.0802-06.2006